Middlesex Orthopedic & Spine Associates is now in Newington! Schedule an appointment today. Physical therapy is now available on Saturdays from 7:00 am to 12:00 pm at 430 Saybrook Road in Middletown and in Marlborough on Mondays and Wednesdays from 7:00 am - 1:00 pm and on Tuesdays and Thursdays from 12:00 pm - 6:00 pm.

Sean J. O’Donnell, MD

Clinical Interests

Hand, Wrist, Elbow, and Shoulder Surgery, Total Joint Replacement, Knee Surgery, Sports Medicine

Located In

Middletown, Westbrook

Dr. Sean O’Donnell is a board-certified orthopedic surgeon who is fellowship-trained in both sports medicine and hand surgery. He cares for patients with a wide range of orthopedic conditions and injuries and has special interests in hand surgery, shoulder surgery, total joint replacement, sports medicine, and knee surgery. His passion, however, is hand surgery, and he currently focuses on hand, wrist, and elbow surgery.

He appreciates how meticulous hand surgery is, and can offer complex surgeries that many general orthopedic surgeons don’t have as much experience in. Still, he takes a conservative approach to surgery, only recommending it when other options have been exhausted.

Dr. O’Donnell chose a career in medicine as he was drawn to science, and he liked the idea of taking care of people. Orthopedics appealed to him as a specialty because of how gratifying it is to be able to fix a problem for a patient.

He started out in sports medicine because he had been an athlete himself, playing football and lacrosse in high school. Dr. O’Donnell then earned his bachelor’s degree from Manhattan College where he played lacrosse and helped to turn the program back into a division sport. He likes working with athletes and active people and helping them get back to the sports they love.

Dr. O’Donnell received his medical degree from Albert Einstein College of Medicine. He then completed his orthopedic surgery residency at Mt. Sinai Medical Center. He completed his fellowship training in Sports Medicine at New England Baptist Hospital in Boston, MA and his fellowship in Hand Surgery at Berufsgenossenschafliches Unfall Krankehaus in Hamburg, Germany.

He is a senior attending physician at Middlesex Hospital and a member of the American Board of Orthopaedic Surgery and American Academy of Orthopedic Surgeons. He has been named a Castle Connolly and Connecticut Magazine Top Doctor since 2022.

Dr. O’Donnell is married and has five children. Two of his sons played Division 1 lacrosse at Marquette University, and his youngest daughter currently competes in Irish Dance. When he has time, he loves to cycle, hike, ski, and travel with his family.

  • Commercial Plans (Including APCN Plus, We do not accept regular APCN)
  • Managed Medicare
Anthem Blue Cross Blue Shield of CT
  • Commercial and Exchange
  • Managed Medicare
Blue Cross Blue Shield (Plans Outside CT)
  • Cards with the “PPO” inside the suitcase logo
CarePartners of Connecticut
  • Managed Medicare (HMO/PPO)
  • Commercial, MetroNY, and LocalPlus
  • Cigna+Oscar, Cigna+MVP
  • Commercial and Exchange (Except “Value” Network)
  • Managed Medicare
Connecticut Medicaid
Connecticut State Workers’ Compensation
  • Emblem Commercial and Exchange (Except for Millennium and Enhanced Care Prime Networks)
  • Managed Medicare (VIP Prime, Bold, Reserve)
Medicare (Including Railroad Medicare)
  • Liberty and Freedom Plans
UHC/NYSHIP/NY Government Empire Plan
United Healthcare
  • All Commercial Plans (Except Indemnity and Compass)
  • Managed Medicare


Sports Medicine Fellow at New England Baptist Hospital, Boston

Hand Surgery Fellow at Berufsgenossenschafliches Unfall Krankehaus, Hamburg, Germany

Medical School

Albert Einstein College of Medicine, New York City


Mt. Sinai Medical Center, New York City


Manhattan College, New York City


St. Joseph Hospital, Denver, CO

  • American Board of Orthopaedic Surgery

  • American Board of Orthopaedic Surgery
  • Member of American Academy of Orthopedic Surgeons

  • Castle Connolly and Connecticut Magazine Top Doctor, 2022-Present

What Our Patients Say About Us